Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 16/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 15/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527317 | 0.88 | ABCB1 (0.51) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL527316 | 0.88 | ABCB1 (0.51) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL646615 | 0.83 | KDM4E (0.52) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL647485 | 0.83 | KDM4E (0.52) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL16240912 | 0.78 | KDM4E (0.50) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL16240911 | 0.78 | KDM4E (0.50) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL9119693 | 0.78 | KDM4E (0.51) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL17947814 | 0.76 | KDM4E (0.49) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL20335167 | 0.76 | KDM4E (0.49) | ALOX5ABCB1ABCG2ABCC1KDM4E | |
| SCHEMBL9119106 | 0.76 | ABCB1 (0.56) | ALOX5ABCB1ABCG2ABCC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927634-B2 | Compositions and methods for treating angiogenesis-related diseases, wounds and cosmetic use of components of Angelica sinensis, and methods of preparation thereof | SUNNY BIODISCOVERY, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100255069-A1 | COMPOSITIONS AND METHODS FOR TREATING ANGIOGENESIS-RELATED DISEASES, WOUNDS AND COSMETIC USE OF COMPONENTS OF ANGELICA SINENSIS, AND METHODS OF PREPARATION THEREOF | SUNNY BIODISCOVERY, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20060068032-A1 | Compositions and methods for treating angiogenesis-related diseases, wounds and cosmetic use of components of Angelica sinensis, and methods of preparation thereof | SUNNY BIODISCOVERY, INC. (US) | 2006-03-30 | — | — | US | disclosed |