SCHEMBL527316

SCHEMBL527316

COc1cc(C=CC(=O)OCCC(C)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C)cc(OC)c1OC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 14/20 0.51
ABCG2 Q9UNQ0 13/20 0.51
ABCC1 P33527 13/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
ALOX5 P09917 1/20 0.49
MET P08581 1/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
HTR1A P08908 1/20 0.47
HPGD P15428 1/20 0.47
HTR2C P28335 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL527317 1.00 ABCB1 (0.51) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL1685990 0.88 ALOX5 (0.49) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL647485 0.85 KDM4E (0.52) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL646615 0.85 KDM4E (0.52) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL6139815 0.83 LMNA (0.43) ABCB1ABCG2ABCC1ALDH1A1LMNA
SCHEMBL645500 0.83 ABCB1 (0.56) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL9440564 0.82 ABCB1 (0.58) ABCB1ABCG2ABCC1ALOX5
SCHEMBL16240911 0.81 KDM4E (0.50) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL16240912 0.81 KDM4E (0.50) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL9119693 0.80 KDM4E (0.51) ABCB1ABCG2ABCC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772224-B2 Perfuming solution stabilized with respect to ultraviolet radiation LVMH RECHERCHE (FR) 2014-07-08 US claimed
US-20130045913-A1 PERFUMING SOLUTION STABILIZED WITH RESPECT TO ULTRAVIOLET RADIATION LVMH RECHERCHE (FR) 2013-02-21 US claimed
JP-9227351-A None JP disclosed
US-20250195384-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2025-06-19 US disclosed
WO-2025125748-A1 COSMETIC COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION COMPRISING A COMBINATION OF LIPOSOLUBLE POLYMER BASED ON MODIFIED PULLULAN AND WATER-SOLUBLE POLYMER LVMH RECHERCHE (FR) 2025-06-19 WO disclosed
EP-4516284-A1 COSMETIC Shiseido Company, Ltd. (JP) 2025-03-05 EP disclosed
WO-2024157751-A1 OIL-IN-WATER TYPE SOLID COSMETIC 株式会社資生堂 2024-08-02 WO disclosed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
US-11964043-B2 Method of emulsification using core-corona type microparticles SHISEIDO COMPANY, LTD. (JP) 2024-04-23 US disclosed
CN-113645942-B Oil-in-water cosmetic and preparation method thereof LVMH研究公司 2024-03-22 CN disclosed
US-11931448-B2 Water-in-oil type emulsion composition SHISEIDO COMPANY, LTD. (JP) 2024-03-19 US disclosed
EP-0688559-B1 Skin anti-ageing composition SHISEIDO CO LTD (JP) 2001-06-20 EP disclosed
EP-1066816-A1 AGENTS PROMOTING LAMININ PRODUCTION IN SKIN CELLS SHISEIDO COMPANY LIMITED (JP) 2001-01-10 EP disclosed
US-6077520-A ANTI-AGING TOPICAL COMPOSITION INCLUDING AT LEAST ONE OF SULFONYLETHYLENEAMINE OR MERCAPTOSULFONYLETHYLENEAMINE COMPOUNDS OF GIVEN FORMULA AND SPECIFIED ULTRAVIOLET LIGHT PROTECTIVE AGENTS SHISEIDO COMPANY, LTD. (JP) 2000-06-20 US disclosed
EP-0972508-A1 EXTRACELLULAR MATRIX PRODUCTION PROMOTER SHISEIDO COMPANY LIMITED (JP) 2000-01-19 EP disclosed
EP-0955035-A1 Body odor preventing composition SHISEIDO COMPANY LIMITED (JP) 1999-11-10 EP disclosed
US-5747049-A AMINOETHYLSULFINIC ACID OR AMINOETHYLTHIOSULFONIC ACID, SUNSCREEN SHISEIDO COMPANY, LTD. (JP) 1998-05-05 US disclosed
JP-H09227351-A UV RAYS ABSORBING SKIN COSMETIC SHISEIDO CO LTD 1997-09-02 JP disclosed
EP-0688559-A1 Skin anti-ageing composition SHISEIDO COMPANY LIMITED (JP) 1995-12-27 EP disclosed
US-5315022-A Sunscreen SHISEIDO COMPANY LTD. (JP) 1994-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11964043-B2 Method of emulsification using core-corona type microparticles LIPA, CORO1A, CLTA ABCB1 1936/4885ABCG2 3610/4885ABCC1 798/4885
US-11931448-B2 Water-in-oil type emulsion composition FAM83A, LIPA, CUTA ABCB1 3019/4885ABCG2 1354/4885ABCC1 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.