Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 11/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647485 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL646615 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL527316 | 0.80 | ABCB1 (0.51) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL527317 | 0.80 | ABCB1 (0.51) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL9440505 | 0.79 | ABCB1 (0.57) | ALOX5ABCB1ABCG2ABCC1 | |
| SCHEMBL20335167 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL17947814 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL9240623 | 0.78 | ATM (0.40) | LMNAHPGD | |
| SCHEMBL1685990 | 0.78 | ALOX5 (0.49) | KDM4EALDH1A1LMNAALOX5ABCB1 | |
| SCHEMBL20958569 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1LMNAALOX5ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0350314-A2 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |