Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845749 | 0.79 | LMNA (0.37) | LMNATRPA1ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL17244348 | 0.78 | LMNA (0.69) | LMNATRPA1ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL4361154 | 0.75 | LMNA (0.41) | LMNATRPA1TSHR | |
| SCHEMBL10688271 | 0.73 | LMNA (0.43) | LMNATRPA1ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL10622106 | 0.66 | — | — | |
| SCHEMBL15150598 | 0.64 | — | — | |
| SCHEMBL17613454 | 0.64 | — | — | |
| SCHEMBL947006 | 0.62 | — | — | |
| SCHEMBL9231482 | 0.61 | LMNA (0.47) | LMNATRPA1ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL16168257 | 0.61 | ALDH1A1 (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087155-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | Albemarle Corporation (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160289527-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORP (US) | 2016-10-06 | — | — | US | disclosed |
| WO-2015100004-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORPORATION (US) | 2015-07-02 | — | — | WO | disclosed |