Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052517 | 0.92 | MAPT (0.39) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL16865127 | 0.91 | MAPT (0.37) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL16865136 | 0.90 | HTT (0.35) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL3786410 | 0.90 | MAPT (0.38) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| Iodide SCHEMBL2682814 | 0.89 | MAPT (0.39) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| Iodide SCHEMBL29072731 | 0.88 | MAPT (0.39) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL3944198 | 0.87 | MAPT (0.36) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL3944197 | 0.87 | MAPT (0.36) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| Iodide SCHEMBL5918788 | 0.86 | MAPT (0.38) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL13983891 | 0.86 | MAPT (0.36) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | BIOTIUM, INC. | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | POLRMT, POLI, EWSR1 | MEN1 2653/4885KMT2A 2294/4885MAPT 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.