Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865119 | 0.90 | MEN1 (0.33) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3664041 | 0.90 | MEN1 (0.38) | HTTMEN1KMT2AMAPTMAPK1 | |
| Iodide SCHEMBL2681957 | 0.89 | MEN1 (0.38) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3939172 | 0.86 | MEN1 (0.39) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3939168 | 0.86 | MEN1 (0.39) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL30865826 | 0.86 | MEN1 (0.39) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6726380 | 0.86 | MEN1 (0.39) | HTTMEN1KMT2AMAPTMAPK1 | |
| Iodide SCHEMBL2683522 | 0.85 | MEN1 (0.38) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3934123 | 0.84 | RAB9A (0.38) | HTTMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3934125 | 0.84 | RAB9A (0.38) | HTTMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | BIOTIUM, INC. | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | POLRMT, POLI, EWSR1 | HTT 211/4885MEN1 2653/4885KMT2A 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.