Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4619723 | 0.98 | KDM4E (0.57) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL18799222 | 0.88 | KDM4E (0.52) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL13645489 | 0.87 | KDM4E (0.64) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL13686278 | 0.85 | KDM4E (0.62) | KDM4EPOLBRECQLBCHEACHE | |
| SCHEMBL53770 | 0.85 | KDM4E (0.52) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| Bromide SCHEMBL50240 | 0.84 | KDM4E (0.55) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL12201138 | 0.82 | KDM4E (0.59) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL6726696 | 0.81 | KDM4E (0.57) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL12849714 | 0.81 | KDM4E (0.57) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL19485776 | 0.81 | KDM4E (0.61) | KDM4EPOLBRECQLHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | BIOTIUM, INC. | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150185182-A1 | NUCLEIC ACID BINDING DYES WITH IMPROVED SAFETY | POLRMT, POLI, EWSR1 | KDM4E 3940/4885POLB 7/4885RECQL 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.