Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1003172 | 0.98 | KDM4E (0.56) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL13645489 | 0.90 | KDM4E (0.64) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL13686278 | 0.88 | KDM4E (0.62) | KDM4EPOLBRECQLBCHEACHE | |
| SCHEMBL12201138 | 0.85 | KDM4E (0.59) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL19485776 | 0.83 | KDM4E (0.61) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL12849714 | 0.83 | KDM4E (0.57) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL16450366 | 0.83 | KDM4E (0.57) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| SCHEMBL12201165 | 0.82 | KDM4E (0.58) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| Iodide SCHEMBL6263617 | 0.82 | KDM4E (0.60) | KDM4EPOLBRECQLHTTSMN1; SMN2 | |
| Bromide SCHEMBL3302575 | 0.82 | KDM4E (0.56) | KDM4EPOLBRECQLHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674102-B2 | Fluorescent dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8674102-B2 | Fluorescent dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130217059-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130217059-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130209994-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-20130209994-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8357801-B2 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-8357801-B2 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20120121509-A1 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | THE GENERAL HOSPITAL CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| US-8173445-B1 | DNA intercalating agents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| WO-2010141833-A2 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | THE GENERAL HOSPITAL CORPORATION (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20090226954-A1 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. | 2009-09-10 | — | — | US | disclosed |
| US-20090226954-A1 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. | 2009-09-10 | — | — | US | disclosed |
| US-7462468-B1 | DNA intercalating agents and methods of use | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2008-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226954-A1 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | SSBP1, IMMT, DNAJA3 | KDM4E 4671/4885POLB 539/4885RECQL 352/4885 |
| US-20120121509-A1 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | CASP3, CASP7, CD47 | KDM4E 3673/4885POLB 4182/4885RECQL 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.