SCHEMBL16865149

SCHEMBL16865149

CC1CC1(C(=O)OCCOC(=O)C1(S(=O)(=O)c2ccccc2)CC1C)S(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
APP P05067 3/20 0.38
ALDH1A1 P00352 4/20 0.38
GAA P10253 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865191 0.86 MAPT (0.41) CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1
SCHEMBL16865205 0.81 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9CYP2C19APP
SCHEMBL16865188 0.78 CYP3A4 (0.47) CYP3A4CYP2C9CYP2C19ALDH1A1GAA
SCHEMBL28848932 0.77 CYP2C19 (0.50) CYP3A4CYP2D6CYP2C9CYP2C19APP
SCHEMBL16865206 0.75 CYP3A4 (0.56) CYP3A4CYP2D6CYP2C9CYP2C19APP
SCHEMBL5674791 0.75 CYP2C19 (0.48) CYP3A4CYP2D6CYP2C9CYP2C19APP
SCHEMBL16865162 0.74 NPSR1 (0.32)
SCHEMBL27182636 0.71 GAA (0.37) CYP2D6GAAL3MBTL1HTTMCOLN3
SCHEMBL16865181 0.70 GAA (0.48) ALDH1A1GAAL3MBTL1MCOLN3KMT2A
SCHEMBL16865202 0.69 ALDH1A1 (0.49) CYP2C19ALDH1A1L3MBTL1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150188193-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed