SCHEMBL16865188

SCHEMBL16865188

COC(=O)C1(S(=O)(=O)c2ccc(S(=O)(=O)C3(C(=O)OC)CC3C)cc2)CC1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
PKM P14618 1/20 0.47
CYP2C19 P33261 1/20 0.47
MMP9 P14780 5/20 0.37
MMP13 P45452 5/20 0.37
MMP1 P03956 4/20 0.37
CA12 O43570 5/20 0.37
CA9 Q16790 5/20 0.37
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA14 Q9ULX7 3/20 0.37
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ATM Q13315 1/20 0.35
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865191 0.92 MAPT (0.41) CYP3A4CYP2C9PKMCYP2C19ALDH1A1
SCHEMBL16865159 0.77 NPSR1 (0.39) TP53NPSR1
SCHEMBL15024695 0.75 CYP3A4 (0.50) CYP3A4CYP2C9PKMCYP2C19ALDH1A1
SCHEMBL10422701 0.69 CYP2C9 (0.46) CYP3A4CYP2C9PKMCYP2C19ALDH1A1
SCHEMBL25316944 0.68 PKM (0.61) CYP3A4CYP2C9PKMCYP2C19MMP9
SCHEMBL4004910 0.67 CYP3A4 (0.60) CYP3A4CYP2C9PKMCYP2C19MMP9
SCHEMBL8527277 0.67 CHRM4 (0.38) CYP3A4CYP2C9PKMCYP2C19CA1
SCHEMBL8498357 0.67 MMP2 (0.37) CYP3A4CYP2C9PKMCYP2C19ALDH1A1
SCHEMBL21760884 0.66 CYP2D6 (0.48) CYP3A4CYP2C9PKMCYP2C19ALDH1A1
SCHEMBL23049642 0.66 CYP3A4 (0.58) CYP3A4CYP2C9PKMCYP2C19MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150188193-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed