Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865331 | 1.00 | PPARA (0.38) | PPARALMNAHTTNPC1ALDH1A1 | |
| SCHEMBL16865339 | 0.89 | PPARA (0.37) | PPARANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17072195 | 0.84 | NFKB1 (0.39) | PPARANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL17072193 | 0.84 | NFKB1 (0.39) | PPARANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL17072194 | 0.84 | NFKB1 (0.39) | PPARANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL16865363 | 0.81 | MAPT (0.37) | PPARALMNAHTTNPC1ALDH1A1 | |
| SCHEMBL16865337 | 0.81 | MAPT (0.37) | PPARALMNAHTTNPC1ALDH1A1 | |
| SCHEMBL16865342 | 0.81 | MAPT (0.37) | PPARALMNAHTTNPC1ALDH1A1 | |
| SCHEMBL16865332 | 0.75 | PPARA (0.43) | PPARALMNAALDH1A1MAPTNOS3 | |
| SCHEMBL16865351 | 0.75 | PPARA (0.43) | PPARALMNAALDH1A1MAPTNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133488-B2 | Synthetic methods and compounds related thereto | UNIVERSITY OF ALASKA FAIRBANKS (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | UNIVERSITY OF ALASKA FAIRBANKS | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | LSS, CYP51A1, FASN | PPARA 191/4885LMNA 1365/4885HTT 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.