Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865363 | 1.00 | MAPT (0.37) | MAPTALDH1A1ADORA1PPARAABCB11 | |
| SCHEMBL16865337 | 1.00 | MAPT (0.37) | MAPTALDH1A1ADORA1PPARAABCB11 | |
| SCHEMBL16865338 | 0.91 | CTDSP1 (0.35) | MAPTALDH1A1PPARACYP1A2CYP3A4 | |
| SCHEMBL17080643 | 0.91 | CTDSP1 (0.35) | MAPTALDH1A1PPARACYP1A2CYP3A4 | |
| SCHEMBL16865359 | 0.91 | CTDSP1 (0.35) | MAPTALDH1A1PPARACYP1A2CYP3A4 | |
| SCHEMBL16865357 | 0.89 | CTDSP1 (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16865358 | 0.89 | CTDSP1 (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16865361 | 0.85 | PTGS2 (0.40) | MAPTALDH1A1MAOBLMNASMN1; SMN2 | |
| SCHEMBL16865340 | 0.81 | PPARA (0.38) | MAPTALDH1A1ADORA1PPARACYP1A2 | |
| SCHEMBL16865331 | 0.81 | PPARA (0.38) | MAPTALDH1A1ADORA1PPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133488-B2 | Synthetic methods and compounds related thereto | UNIVERSITY OF ALASKA FAIRBANKS (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | UNIVERSITY OF ALASKA FAIRBANKS | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | LSS, CYP51A1, FASN | MAPT 3810/4885ALDH1A1 506/4885ADORA1 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.