SCHEMBL16865398

SCHEMBL16865398

CN1C(=O)N(C)C(=O)C(O)(Cc2ccccc2)C1=O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.45
RAD52 P43351 1/20 0.42
ALDH1A1 P00352 5/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
BACE1 P56817 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
EP300 Q09472 2/20 0.39
CREBBP Q92793 1/20 0.39
HIF1A Q16665 1/20 0.39
ATM Q13315 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865432 0.88 RAD52 (0.38) RAD52ALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL10645739 0.83 ELANE (0.56) ELANEALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL17294194 0.81 ELANE (0.41) ELANEALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL4917193 0.76 ELANE (0.50) ELANEALDH1A1SMN1; SMN2NPSR1ATM
SCHEMBL16865437 0.74 ALDH1A1 (0.53) ELANEALDH1A1MAPTBACE1ATM
SCHEMBL16865394 0.73 ELANE (0.41) ELANEALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL16865428 0.72 MMP9 (0.56) ELANESMN1; SMN2ATM
SCHEMBL16865422 0.71 ELANE (0.39) ELANEALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL16865433 0.71 ELANE (0.47) ELANEALDH1A1SMN1; SMN2NPSR1LMNA
SCHEMBL16865413 0.70 ELANE (0.50) ELANEALDH1A1MAPTHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885RAD52 1215/4885ALDH1A1 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.