SCHEMBL16865417

SCHEMBL16865417

COCCNC1(Cc2ccccc2)C(=O)N(Cc2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CTSG P08311 2/20 0.36
F2 P00734 1/20 0.36
PLG P00747 1/20 0.36
CMA1 P23946 1/20 0.36
CTRC Q99895 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
PRTN3 P24158 1/20 0.34
NR3C2 P08235 2/20 0.34
NPC1 O15118 1/20 0.34
CYP3A4 P08684 1/20 0.34
BRD4 O60885 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865450 0.82 ELANE (0.49) ELANENPSR1ALDH1A1MAPK1CYP3A4
SCHEMBL17716265 0.73 ELANE (0.72) ELANENPSR1CTSGF2PLG
SCHEMBL16865386 0.72 ELANE (0.51) ELANENPSR1CTSGF2PLG
SCHEMBL16865413 0.71 ELANE (0.50) ELANENPSR1CTSGF2PLG
SCHEMBL16865411 0.71 ELANE (0.50) ELANENPSR1CTSGF2PLG
SCHEMBL16865433 0.70 ELANE (0.47) ELANENPSR1ALDH1A1CYP3A4KDM4E
SCHEMBL16865446 0.68 NPSR1 (0.51) ELANENPSR1CTSGF2PLG
SCHEMBL16865419 0.68 NPSR1 (0.54) ELANENPSR1CTSGF2PLG
SCHEMBL16865444 0.67 EP300 (0.42) ELANENPSR1CMA1ALDH1A1NPC1
SCHEMBL16865401 0.67 ELANE (0.40) ELANENPSR1ALDH1A1NR3C2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885NPSR1 2710/4885CTSG 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.