SCHEMBL16865444

SCHEMBL16865444

COc1ccc(SC2(Cc3ccccc3)C(=O)N(Cc3ccccc3)C(=O)N(c3ccccc3)C2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.42
CMA1 P23946 1/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 1/20 0.42
ELANE P08246 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
PIM1 P11309 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR1A P08908 1/20 0.40
HTR7 P34969 1/20 0.40
HTR6 P50406 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865396 0.79 ELANE (0.53) ALDH1A1ELANENPSR1MEN1KMT2A
SCHEMBL16865416 0.74 ELANE (0.46) CMA1MAPTALDH1A1ELANEMEN1
SCHEMBL17716265 0.71 ELANE (0.72) CMA1ALDH1A1ELANENPSR1MEN1
SCHEMBL16865386 0.70 ELANE (0.51) EP300CMA1ALDH1A1ELANENPSR1
SCHEMBL7449650 0.69 CMA1 (0.56) EP300CMA1MAPTALDH1A1ELANE
SCHEMBL16865413 0.69 ELANE (0.50) CMA1MAPTALDH1A1ELANENPSR1
SCHEMBL16865411 0.69 ELANE (0.50) EP300CMA1ALDH1A1ELANENPSR1
SCHEMBL16865404 0.68 MEN1 (0.47) ELANEMEN1KMT2A
SCHEMBL15131567 0.68 EP300 (0.60) EP300CMA1PIM1MEN1KMT2A
SCHEMBL16865417 0.67 ELANE (0.43) CMA1ALDH1A1ELANENPSR1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 EP300 286/4885CMA1 1276/4885MAPT 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.