SCHEMBL16865429

SCHEMBL16865429

Cc1cccc(N2C(=O)NC(=O)C(O)(c3ccccc3)C2=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ALDH1A1 P00352 7/20 0.46
HSP90AA1 P07900 1/20 0.45
MGLL Q99685 1/20 0.45
KDM4E B2RXH2 2/20 0.42
OPRM1 P35372 1/20 0.41
OPRL1 P41146 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
HSD11B1 P28845 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HPGD P15428 2/20 0.40
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
THRB P10828 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5659353 0.69 ALDH1A1 (0.40) MAPTL3MBTL1HSD17B10ALDH1A1HSP90AA1
SCHEMBL16865393 0.68 ELANE (0.47) ALDH1A1MGLLGAA
SCHEMBL16865391 0.67 GAA (0.41) MAPTHSD17B10ALDH1A1MGLLKDM4E
SCHEMBL18468244 0.67 MAPT (0.60) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL9802946 0.65 MAPT (1.00) MAPTL3MBTL1HSD17B10HSP90AA1MGLL
SCHEMBL259386 0.65 MEN1 (0.67) L3MBTL1ALDH1A1HSP90AA1MGLLKDM4E
SCHEMBL30777591 0.65 MEN1 (0.67) L3MBTL1ALDH1A1HSP90AA1MGLLKDM4E
SCHEMBL30758580 0.65 MEN1 (0.67) L3MBTL1ALDH1A1HSP90AA1MGLLKDM4E
SCHEMBL4918801 0.64 KDM4E (0.42) MAPTHSD17B10ALDH1A1KDM4EOPRM1
SCHEMBL29644711 0.64 HSP90AA1 (0.56) MAPTL3MBTL1HSD17B10ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 MAPT 1367/4885L3MBTL1 700/4885HSD17B10 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.