SCHEMBL16865779

SCHEMBL16865779

CCn1c2ccccc2c2ccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.50
NPY5R Q15761 4/20 0.49
RAC2 P15153 1/20 0.47
RAC3 P60763 1/20 0.47
CDC42 P60953 1/20 0.47
RAC1 P63000 1/20 0.47
PTGER4 P35408 6/20 0.45
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
HBB P68871 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CNR2 P34972 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865778 0.92 NPY5R (0.58) NPY5RRAC2RAC3CDC42RAC1
SCHEMBL14728104 0.87 NPY5R (0.53) KDM1ANPY5RRAC2RAC3CDC42
SCHEMBL13620583 0.85 KDM4E (0.54) KDM1ANPY5RRAC2RAC3CDC42
SCHEMBL13620587 0.85 KDM4E (0.54) KDM1ANPY5RRAC2RAC3CDC42
SCHEMBL17809435 0.84 KDM4E (0.58) NPY5RRAC2RAC3CDC42RAC1
SCHEMBL22870164 0.84 KDM4E (0.56) KDM1ANPY5RKDM4EALDH1A1MAPT
SCHEMBL5999686 0.84 KDM4E (0.59) KDM1ANPY5RKDM4EALDH1A1MAPT
SCHEMBL14728099 0.83 NPY5R (0.47) KDM1ANPY5RRAC2RAC3CDC42
SCHEMBL16726746 0.83 PTGER4 (0.53) NPY5RRAC2RAC3CDC42RAC1
SCHEMBL21889082 0.82 KDM1A (0.51) KDM1ANPY5RRAC2RAC3CDC42

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10396294-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-27 US disclosed
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-07-02 US disclosed
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10396294-B2 Carbazole compound and organic light-emitting device including the same CRY1, CYP1A1, CYP1B1 KDM1A 753/4885NPY5R 3015/4885RAC2 2859/4885
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 KDM1A 753/4885NPY5R 3015/4885RAC2 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.