Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925977 | 0.82 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1GRM5CA2KDM4E | |
| SCHEMBL28284252 | 0.82 | HPGD (0.55) | ALDH1A1GRM5CA2RBBP9TSHR | |
| SCHEMBL28177282 | 0.77 | GAA (0.49) | ALDH1A1GRM5RBP4RBBP9TSHR | |
| SCHEMBL28284253 | 0.77 | GAA (0.49) | ALDH1A1GRM5RBP4RBBP9TSHR | |
| SCHEMBL5130274 | 0.74 | RBP4 (0.51) | ALDH1A1GRM5RBP4SMN1; SMN2 | |
| SCHEMBL7953700 | 0.73 | ALDH1A1 (0.50) | TDP1L3MBTL1ALDH1A1GRM5CA2 | |
| SCHEMBL4504302 | 0.73 | ALDH1A1 (0.50) | TDP1L3MBTL1ALDH1A1GRM5CA2 | |
| SCHEMBL7960313 | 0.72 | TDP1 (0.61) | TDP1L3MBTL1ALDH1A1CA2KDM4E | |
| SCHEMBL970704 | 0.72 | RBP4 (0.50) | ALDH1A1RBP4RBBP9SMN1; SMN2 | |
| SCHEMBL3178325 | 0.72 | DGAT1 (0.54) | TDP1L3MBTL1ALDH1A1GRM5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |