Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871130 | 0.83 | CASR (0.46) | CASRMEN1MAPTKMT2ASLC13A5 | |
| SCHEMBL16871360 | 0.77 | CASR (0.48) | CASRSMN1; SMN2NPC1RAB9APTPN1 | |
| SCHEMBL16871195 | 0.72 | KCNA5 (0.43) | CASRMEN1MAPTKMT2ANPC1 | |
| SCHEMBL3640747 | 0.69 | CASR (0.45) | CASRMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30892233 | 0.68 | CASR (0.43) | CASRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29281783 | 0.68 | CASR (0.43) | CASRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28710154 | 0.67 | CASR (0.52) | CASRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29449583 | 0.67 | CASR (0.52) | CASRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29033640 | 0.67 | CASR (0.46) | CASRMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29033625 | 0.67 | CASR (0.43) | CASRMEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | AKR1C3, DCXR, AKR1C2 | CASR 3720/4885FSCN1 2778/4885MEN1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.