Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 10/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871130 | 0.87 | CASR (0.46) | CASRMEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL17895625 | 0.82 | CASR (0.44) | KCNA5NPC1RAB9ACASRSCD | |
| SCHEMBL11493107 | 0.78 | KCNA5 (0.59) | KCNA5CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16871050 | 0.75 | CASR (0.45) | CASRMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL16871347 | 0.75 | MAPT (0.47) | NPC1RAB9ACASRMEN1KMT2A | |
| SCHEMBL16871004 | 0.72 | CASR (0.43) | NPC1RAB9ACASRMEN1KMT2A | |
| SCHEMBL11784207 | 0.70 | KCNA5 (0.47) | KCNA5CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17895705 | 0.70 | RORC (0.39) | KCNA5NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29033640 | 0.69 | CASR (0.46) | NPC1RAB9ACASRMEN1KMT2A | |
| SCHEMBL29033625 | 0.69 | CASR (0.43) | NPC1CASRMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | AKR1C3, DCXR, AKR1C2 | KCNA5 1089/4885NPC1 2922/4885RAB9A 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.