Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870971 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL16871508 | 0.89 | L3MBTL1 (0.46) | L3MBTL1MTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL16871593 | 0.89 | L3MBTL1 (0.46) | L3MBTL1MTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL16871463 | 0.87 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2POLBROCK2ROCK1 | |
| SCHEMBL16871416 | 0.87 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2POLBROCK2ROCK1 | |
| SCHEMBL16871042 | 0.85 | AOC3 (0.43) | L3MBTL1SMN1; SMN2POLBROCK2ROCK1 | |
| SCHEMBL16871038 | 0.85 | AOC3 (0.43) | L3MBTL1SMN1; SMN2POLBROCK2ROCK1 | |
| SCHEMBL16871045 | 0.81 | KMT2A (0.53) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16871057 | 0.81 | KMT2A (0.53) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16871044 | 0.81 | ADRB1 (0.42) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183727-A1 | METHOD FOR THE PREPARATION OF 1-ARYL-1-ALKYL-2-ALKYL-3-DIALKYLAMINOPROPANE COMPOUNDS | SIEGFRIED AG (CH) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183727-A1 | METHOD FOR THE PREPARATION OF 1-ARYL-1-ALKYL-2-ALKYL-3-DIALKYLAMINOPROPANE COMPOUNDS | CYP3A43, CYP1A2, CYP2C8 | L3MBTL1 1979/4885MTNR1A 444/4885MTNR1B 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.