Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368521 | 1.00 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL13917924 | 0.86 | TP53 (0.51) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL13554388 | 0.82 | TP53 (0.49) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL28364396 | 0.80 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL28364398 | 0.80 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL13932254 | 0.78 | NPC1 (0.46) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL15991880 | 0.77 | CYP2C9 (0.53) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL13554386 | 0.77 | NPC1 (0.44) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL13917922 | 0.77 | CTDSP1 (0.45) | NPC1RAB9ANCOA1NCOA3KMT2A | |
| SCHEMBL15991796 | 0.76 | KMT2A (0.37) | NPC1RAB9ANCOA1NCOA3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015097313-A1 | METAL CHELATION-BASED FLUORESCENT PROBES FOR PROTEIN OR OTHER BIOMOLECULE LABELING IN CELLS | THE UNIVERSITY OF HONG KONG (CN) | 2015-07-02 | — | — | WO | disclosed |