Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364398 | 1.00 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3SRC | |
| SCHEMBL13917924 | 0.84 | TP53 (0.51) | NPC1RAB9ANCOA1NCOA3MAPT | |
| SCHEMBL13554388 | 0.82 | TP53 (0.49) | NPC1RAB9ANCOA1NCOA3MAPT | |
| SCHEMBL13917915 | 0.81 | NPC1 (0.42) | NPC1RAB9ANCOA1NCOA3TP53 | |
| SCHEMBL13554386 | 0.80 | NPC1 (0.44) | NPC1RAB9ANCOA1NCOA3TP53 | |
| SCHEMBL28368521 | 0.80 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3MAPT | |
| SCHEMBL16871074 | 0.80 | NPC1 (0.41) | NPC1RAB9ANCOA1NCOA3MAPT | |
| SCHEMBL13932254 | 0.79 | NPC1 (0.46) | NPC1RAB9ANCOA1NCOA3TP53 | |
| SCHEMBL29355874 | 0.79 | DUSP3 (0.56) | NPC1RAB9ANCOA1NCOA3SRC | |
| SCHEMBL691948 | 0.79 | DUSP3 (0.56) | NPC1RAB9ANCOA1NCOA3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106461649-B | Metal chelate based fluorescent probes for labeling proteins or other biomolecules in cells | 香港大学 | 2020-03-17 | — | — | CN | disclosed |