⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951226 | 0.81 | CA2 (0.30) | — | |
| SCHEMBL3074860 | 0.72 | — | — | |
| SCHEMBL8195640 | 0.70 | — | — | |
| SCHEMBL14595656 | 0.68 | — | — | |
| SCHEMBL13771430 | 0.67 | — | — | |
| SCHEMBL17826854 | 0.67 | — | — | |
| SCHEMBL3077677 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL27769840 | 0.65 | LMNA (0.38) | — | |
| SCHEMBL3078435 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL28544682 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221868579-U | Multistage grinding device is used in production of O-methyl-N-methyl isourea | 山西裕英永旭新材料有限责任公司 | 2024-10-22 | — | — | CN | claimed |
| CN-221868579-U | Multistage grinding device is used in production of O-methyl-N-methyl isourea | 山西裕英永旭新材料有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-221868579-U | Multistage grinding device is used in production of O-methyl-N-methyl isourea | 山西裕英永旭新材料有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-221868579-U | Multistage grinding device is used in production of O-methyl-N-methyl isourea | 山西裕英永旭新材料有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| US-20230203086-A1 | RIBONUCLEIC ACID PURIFICATION | ARES CAPITAL CORPORATION, AS AGENT | 2023-06-29 | — | — | US | disclosed |
| US-20170328909-A1 | APTAMERS AND DIAGNOSTIC METHODS FOR DETECTING THE EGF RECEPTOR | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2017-11-16 | — | — | US | disclosed |
| US-20170260531-A1 | Aptamers to PDGF and VEGF and Their Use in Treating PDGF and VEGF Mediated Conditions | SOMALOGIC OPERATING CO. INC. | 2017-09-14 | — | — | US | disclosed |
| US-20170247702-A1 | PDGF and VEGF Aptamers Having Improved Stability and Their Use in Treating PDGF and VEGF Mediated Diseases and Disorders | SOMALOGIC OPERATING CO. INC. | 2017-08-31 | — | — | US | disclosed |
| US-9701967-B2 | Aptamers to PDGF and VEGF and their use in treating PDGF and VEGF mediated conditions | SOMALOGIC, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9695424-B2 | PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and disorders | SOMALOGIC, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| EP-1391454-A1 | Substituted benzamide compounds with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1195372-A1 | N-heterocyclic substituted benzamide derivatives with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6156766-A | Benzamide compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0641781-B1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5958944-A | TREATMENT OF CIRCULATORY DISEASES IN CORONARY, CEREBRAL, RENAL AND PERIPHERAL ARTERIES, AS A THERAPEUTIC AGENT FOR HYPERTENSION, ANGINA PECTORIS, AND RENAL AND PERIPHERAL CIRCULATION DISORDER, ANTIASTHMATIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0757038-A1 | BENZAMIDE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5478838-A | Treating hypertension, angina pectoris, asthma, improving peripheral circulation | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0641781-A1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-4110445-A | METHOD FOR ANTAGONIZING ALDOSTERONIC ACTION AND INDUCING DIURESIS BY ADMINISTERING A TETRASUBSTITUTED IMIDAZOLIDINE | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4044021-A | Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism | AMERICAN CYANAMID COMPANY (US) | 1977-08-23 | — | — | US | disclosed |