Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271364 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL16486276 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL18323017 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL17988794 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL12776570 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL1440304 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL3434449 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL1408791 | 0.70 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL179057 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL179056 | 0.70 | KDM4E (0.36) | KDM4EALDH1A1MAPTGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103438-A2 | ONCOLYTIC VIRUS ADJUNCT THERAPY WITH AGENTS THAT INCREASE VIRUS INFECTIVITY | GENELUX CORPORATION (US) | 2015-07-09 | — | — | WO | disclosed |