Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16877576 | 0.95 | CXCR4 (0.35) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL16878327 | 0.93 | ALDH1A1 (0.36) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL7650866 | 0.93 | CXCR4 (0.30) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL15399963 | 0.89 | — | — | |
| SCHEMBL16877799 | 0.88 | CXCR4 (0.30) | CXCR4SMN1; SMN2ALDH1A1 | |
| Pyrrolidine SCHEMBL27162253 | 0.88 | ALDH1A1 (0.36) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL23509080 | 0.87 | CXCR4 (0.33) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL255188 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL30282623 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL2236109 | 0.85 | KCNH2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326157-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-10 | — | — | US | disclosed |
| WO-2015103583-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326157-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | MGAM, BPGM, MRPL21 | CXCR4 2852/4885SMN1; SMN2 3006/4885ALDH1A1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.