Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879704 | 1.00 | MAPT (0.56) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11016312 | 0.85 | MEN1 (0.63) | MAPTRAB9ANPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11755337 | 0.81 | NPC1 (0.60) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6326856 | 0.79 | POLB (0.52) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6941009 | 0.79 | MEN1 (0.57) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19917189 | 0.78 | SMN1; SMN2 (0.46) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL2256077 | 0.77 | MAPT (0.62) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL1666596 | 0.77 | MAPT (0.62) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL20603943 | 0.77 | MAPT (0.65) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9687003 | 0.76 | LMNA (0.54) | MAPTRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089966-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | Beaufour Ipsen Tianjin Pharmaceutical Co., Ltd (CN) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015100609-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | BEAUFOUR IPSEN TIANJIN PHARMACEUTICAL CO., LTD (CN) | 2015-07-09 | — | — | WO | disclosed |