Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | SETDB1 | Q15047 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881448 | 0.79 | BACE1 (0.37) | BACE1TACR1 | |
| SCHEMBL16881274 | 0.77 | BACE1 (0.35) | BACE1 | |
| SCHEMBL28821097 | 0.76 | BACE1 (0.38) | BACE1MTNR1ATACR1MTNR1B | |
| SCHEMBL16880557 | 0.76 | BACE1 (0.34) | BACE1 | |
| SCHEMBL3081717 | 0.76 | KDM5A (0.37) | BACE1P2RX7 | |
| SCHEMBL20436600 | 0.75 | BACE1 (0.43) | BACE1TACR1 | |
| SCHEMBL16880571 | 0.74 | BACE1 (0.39) | BACE1TACR1 | |
| SCHEMBL1751532 | 0.74 | TSHR (0.45) | BACE1P2RX7TACR1 | |
| SCHEMBL29788857 | 0.74 | CA2 (0.52) | P2RX7BDKRB1 | |
| SCHEMBL16881366 | 0.74 | KMT2A (0.44) | P2RX7BDKRB1NPSR1MTNR1ASETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |