SCHEMBL509278

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18019821	0.88	DYRK1A (0.50)	DYRK1ANAMPTCYP3A4L3MBTL1ALDH1A1
	SCHEMBL16880569	0.86	CYP2C9 (0.43)	CYP2C19CYP2C9DYRK1ANAMPTKMT2A
	SCHEMBL510089	0.84	DYRK1A (0.51)	CYP2C19CYP2C9DYRK1ANAMPTKMT2A
	SCHEMBL24139848	0.84	DYRK1A (0.50)	DYRK1ANAMPTCYP3A4GAAMAPT
	SCHEMBL16881353	0.82	NAMPT (0.42)	CYP2C19CYP2C9DYRK1ANAMPTKMT2A
	SCHEMBL16020299	0.81	DYRK1A (0.50)	CYP2C9DYRK1ANAMPTCYP3A4GAA
	SCHEMBL3905352	0.80	HTT (0.59)	NAMPTKMT2ACYP3A4CYP1A2GAA
	SCHEMBL29382818	0.80	CYP2C19 (0.69)	CYP2C19CYP2C9KMT2ACYP3A4CYP1A2
	SCHEMBL28585768	0.80	CYP2C19 (0.69)	CYP2C19CYP2C9KMT2ACYP3A4CYP1A2
	SCHEMBL4398673	0.80	CYP2C19 (0.54)	CYP2C19CYP2C9NAMPTKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.