Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882976 | 0.88 | ESR1 (0.46) | ALDH1A1LMNAPDK2ESR1ESR2 | |
| SCHEMBL9172910 | 0.87 | PDK2 (0.55) | ALDH1A1LMNAPDK2ESR1ESR2 | |
| SCHEMBL11892509 | 0.83 | PDK2 (0.42) | HPGDALDH1A1LMNAPDK2ESR1 | |
| SCHEMBL8984549 | 0.81 | MAPT (0.53) | HPGDALDH1A1LMNAL3MBTL1PDK2 | |
| SCHEMBL13668308 | 0.77 | PDK2 (0.48) | HPGDALDH1A1LMNAPDK2ESR1 | |
| SCHEMBL7048312 | 0.76 | MAPT (0.61) | LMNAPDK2ESR1ESR2MEN1 | |
| SCHEMBL29579855 | 0.76 | MAPT (0.61) | LMNAPDK2ESR1ESR2MEN1 | |
| SCHEMBL27951063 | 0.75 | MEN1 (0.53) | ALDH1A1LMNAPDK2ESR1ESR2 | |
| Trifluoromethanesulfonic Acid SCHEMBL1990220 | 0.75 | PDK2 (0.43) | PDK2ESR1ESR2S100A4 | |
| SCHEMBL20198312 | 0.75 | MAOA (0.44) | LMNAL3MBTL1PDK2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186799-B1 | AROMATIC SULFONIUM SALT COMPOUND | ADEKA CORP (JP) | 2015-07-08 | — | — | EP | disclosed |