Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905646 | 0.96 | MAOA (0.50) | MAOAMAOBMEN1MAPTKMT2A | |
| SCHEMBL15498442 | 0.90 | MAOA (0.55) | MAOAMAOBMAPTSMN1; SMN2BCL2 | |
| SCHEMBL16882976 | 0.85 | ESR1 (0.46) | MAOAMAOBMEN1MAPTKMT2A | |
| SCHEMBL25052760 | 0.82 | KDM4E (0.41) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL23372165 | 0.81 | PDE7A (0.35) | MAOAMAOBMEN1MAPTKMT2A | |
| SCHEMBL16882977 | 0.81 | PDE4D (0.43) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL28991408 | 0.81 | MAOA (0.42) | MAOAMAOBMEN1MAPTKMT2A | |
| SCHEMBL19773709 | 0.81 | KDM4E (0.40) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL20198231 | 0.79 | PDK2 (0.33) | MAOAMAOBPDK2 | |
| SCHEMBL29591921 | 0.78 | MAOA (0.47) | MAOAMAOBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |