SCHEMBL16883109

SCHEMBL16883109

c1ccc(-c2cccc(-c3ccccc3N(c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccc4c5ccccc5c5ccccc5c4c3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
PRKDC P78527 2/20 0.37
F9 P00740 1/20 0.34
PARP14 Q460N5 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
LIMK1 P53667 4/20 0.31
DNPH1 O43598 1/20 0.31
PIM3 Q86V86 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16883099 0.97 ALOX5 (0.47) ALOX5PRKDCF9PARP14TNKS
SCHEMBL16883137 0.96 ALOX5 (0.48) ALOX5PRKDCF9PARP14TNKS
SCHEMBL16883147 0.92 ALOX5 (0.45) ALOX5PRKDCF9PARP14TNKS
SCHEMBL22136359 0.92 ALOX5 (0.48) ALOX5PRKDCF9PARP14TNKS
SCHEMBL16883132 0.92 ALOX5 (0.49) ALOX5PRKDCF9PARP14TNKS
SCHEMBL23239492 0.92 ALOX5 (0.46) ALOX5PRKDCF9PARP14DNPH1
SCHEMBL23236995 0.91 ALOX5 (0.45) ALOX5PRKDCF9PARP14
SCHEMBL18212056 0.90 ALOX5 (0.47) ALOX5PRKDCF9PARP14TNKS
SCHEMBL24472073 0.90 ALOX5 (0.50) ALOX5PRKDCF9PARP14TNKS
SCHEMBL24472450 0.90 ALOX5 (0.50) ALOX5PRKDCF9PARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 EP disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
EP-2891653-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2015-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885F9 4636/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885F9 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.