SCHEMBL16883116

SCHEMBL16883116

Cc1ccccc1-c1ccc(N(c2ccc(-c3cccc4c3oc3ccccc34)cc2)c2ccc3c4ccccc4c4ccccc4c3c2)cc1C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.45
PRKDC P78527 4/20 0.37
GGPS1 O95749 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
TNKS O95271 1/20 0.32
MAOB P27338 1/20 0.32
ATM Q13315 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PGR P06401 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17547775 0.94 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL17547772 0.92 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL15179939 0.91 ALOX5 (0.42) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883028 0.89 ALOX5 (0.55) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883071 0.89 ALOX5 (0.55) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883210 0.89 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883142 0.88 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883191 0.88 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL17734660 0.88 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2TNKS
SCHEMBL16883235 0.87 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 EP disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
EP-2891653-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2015-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885GGPS1 4411/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885GGPS1 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.