SCHEMBL16883146

SCHEMBL16883146

c1ccc(-c2ccc(N(c3ccc(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)cc3)c3ccc4c5ccccc5c5ccccc5c4c3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
GGPS1 O95749 1/20 0.41
PRKDC P78527 8/20 0.41
PTGES2 Q9H7Z7 1/20 0.39
CDC14B O60729 1/20 0.35
CDC14A Q9UNH5 1/20 0.35
PLA2G2A P14555 2/20 0.35
PLA2G4A P47712 2/20 0.35
ALDH1A1 P00352 3/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CA P42336 2/20 0.34
PIK3CB P42338 2/20 0.34
PIK3CG P48736 2/20 0.34
KDM4E B2RXH2 2/20 0.34
BRD4 O60885 2/20 0.34
BRD2 P25440 2/20 0.34
BRD3 Q15059 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PDE2A O00408 1/20 0.34
PIK3C2A O00443 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19537666 1.00 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16883124 1.00 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16303054 1.00 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16883232 0.97 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL21432092 0.97 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16883127 0.97 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL15179917 0.97 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL15179838 0.97 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16883135 0.97 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL16883149 0.97 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2CDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 EP disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
EP-2891653-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2015-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALOX5 2443/4885GGPS1 4411/4885PRKDC 4736/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALOX5 2443/4885GGPS1 4411/4885PRKDC 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.