Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884330 | 0.83 | TRPV6 (0.56) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL16884338 | 0.80 | SCN9A (0.46) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL15029146 | 0.80 | MEN1 (0.61) | TRPV6MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11688986 | 0.80 | P2RX7 (0.63) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL3360521 | 0.80 | TRPV6 (0.56) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL3360559 | 0.80 | TRPV6 (0.67) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL19840794 | 0.80 | TRPV6 (0.67) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| Hydrochloric Acid SCHEMBL11688866 | 0.79 | P2RX7 (0.61) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL16884192 | 0.78 | EPHX2 (0.44) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL16884335 | 0.78 | CNR2 (0.46) | TRPV6MEN1KMT2ASMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | HAVCR2, HDLBP, HSP90B1 | TRPV6 3648/4885MEN1 3879/4885KMT2A 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.