SCHEMBL168847

SCHEMBL168847

CN1C(=O)CCC1=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624312 0.82 GSK3A (0.37)
SCHEMBL11683522 0.78
SCHEMBL9020270 0.78
SCHEMBL27941 0.78
Methane SCHEMBL14957784 0.76
Dimethylamine SCHEMBL9278029 0.71 BRD4 (0.38)
SCHEMBL11835650 0.70 CHRM2 (0.34)
SCHEMBL29211489 0.69 FAAH (0.40)
SCHEMBL18872066 0.69
SCHEMBL17584876 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556742-A PHOSPHINE AND HALOGEN LIGANDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-17 US claimed
US-4068071-A DISULFIDING, SOLVOLYSIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1978-01-10 US claimed
US-4001025-A SILVER SULFIDE, DIGESTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-01-04 US claimed
JP-63095240-A None JP disclosed
US-20240352056-A1 Improved methods for production of cyclic guanosine-monophosphate analogues MIRECA MEDICINES GMBH (DE) 2024-10-24 US disclosed
CN-117999269-A Improved process for producing cyclic guanosine monophosphate analogues 米雷卡医药有限公司 2024-05-07 CN disclosed
EP-2611813-B1 DITHIIN-TETRA(THIO) CARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI BAYER IP GMBH (DE) 2015-01-21 EP disclosed
US-8524916-B2 Dithiinetetra(thio)carboximides BAYER CROPSCIENCE AG (DE) 2013-09-03 US disclosed
EP-1810969-B1 ARYLOXY-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES MSD KK (JP) 2013-08-07 EP disclosed
EP-2611813-A1 DITHIIN-TETRA(THIO) CARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI Bayer Intellectual Property GmbH (DE) 2013-07-10 EP disclosed
US-20120225923-A1 Dithiinetetra(thio)carboximides BAYER CROPSCIENCE AG (DE) 2012-09-06 US disclosed
EP-0762195-A1 Sensitization of silver halide emulsions with noble metal complexes Imation Corp. (US) 1997-03-12 EP disclosed
US-5556742-A PHOSPHINE AND HALOGEN LIGANDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-17 US disclosed
EP-0184173-B1 13beta-milbemycine derivatives for the control of ectoparasites and endoparasites in plants and animals CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
JP-S6395240-A LOW HEAT-GENERATION RUBBER COMPOSITION BRIDGESTONE CORP 1988-04-26 JP disclosed
US-4696945-A 13β-milbemycin derivatives for controlling ecto- and endoparasites of plants and animals CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
EP-0184173-A2 13beta-milbemycine derivatives for the control of ectoparasites and endoparasites in plants and animals CIBA-GEIGY AG (CH) 1986-06-11 EP disclosed
US-4068071-A DISULFIDING, SOLVOLYSIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1978-01-10 US disclosed
US-4001025-A SILVER SULFIDE, DIGESTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-01-04 US disclosed