Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168847 | 0.82 | — | — | |
| SCHEMBL23153195 | 0.73 | GSK3A (0.35) | GSK3AGSK3BBRD4BRD2 | |
| SCHEMBL11683522 | 0.73 | — | — | |
| SCHEMBL472573 | 0.69 | GSK3A (0.42) | GSK3AGSK3BBRD4BRD2 | |
| SCHEMBL17584876 | 0.68 | — | — | |
| SCHEMBL7945735 | 0.67 | — | — | |
| SCHEMBL23894741 | 0.67 | GSK3A (0.38) | GSK3AGSK3BBRD4BRD2 | |
| SCHEMBL1304391 | 0.65 | — | — | |
| SCHEMBL14872073 | 0.65 | — | — | |
| SCHEMBL27371547 | 0.64 | GSK3A (0.37) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10045719-A | — | — | None | — | — | JP | disclosed |
| JP-H1045719-A | CYCLIC BETA-KETOTHIOAMIDE DERIVATIVE | AGENCY OF IND SCIENCE & TECHNOL | 1998-02-17 | — | — | JP | disclosed |
| US-5677444-A | Method for the preparation of β-ketothioamide compound | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1997-10-14 | — | — | US | disclosed |