Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256670 | 0.84 | — | — | |
| Propionic Acid SCHEMBL28122151 | 0.80 | FFAR3 (0.53) | PLGPLATLMNATHRATHRB | |
| SCHEMBL10067857 | 0.79 | PLG (0.61) | PLGPLATLMNATHRATHRB | |
| SCHEMBL15712882 | 0.79 | CYP2C9 (0.42) | PLGPLATLMNATHRATHRB | |
| SCHEMBL11933775 | 0.79 | PLG (0.61) | PLGPLATLMNATHRATHRB | |
| SCHEMBL19362610 | 0.78 | PRKCA (0.45) | ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL15478106 | 0.78 | PLG (0.38) | PLGPLATLMNATHRATHRB | |
| SCHEMBL16892307 | 0.78 | PLG (0.38) | PLGPLATLMNATHRATHRB | |
| SCHEMBL17614875 | 0.77 | PLG (0.34) | PLGPLATLMNATHRATHRB | |
| SCHEMBL10479667 | 0.77 | CYP2C9 (0.41) | PLGPLATLMNATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103509-A1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |