Propionic Acid

Propionic Acid

SCHEMBL28122151

CCC(=O)O.OCC1CC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.53
LMNA P02545 2/20 0.39
PLG P00747 1/20 0.39
PLAT P00750 1/20 0.39
MAPT P10636 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
NR1H2 P55055 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
SLC6A1 P30531 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRB2 P47870 2/20 0.32
SLC6A12 P48065 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL27326892 0.86 GABRA5 (0.50) FFAR3SLC6A1GABRA5GABRB2SLC6A12
Acetic Acid SCHEMBL2479593 0.83
Bicarbonate SCHEMBL5274866 0.83 PLG (0.40) LMNAPLGPLATESR1ESR2
Succinic Acid SCHEMBL30288581 0.81 LMNA (0.50) FFAR3LMNAPLGPLATMAPT
Malonic Acid SCHEMBL30288560 0.81 LDHA (0.50) LMNAPLGPLATESR1ESR2
Acetone SCHEMBL9562373 0.80
SCHEMBL16887693 0.80 PLG (0.37) LMNAPLGPLATESR1ESR2
Acetic Acid SCHEMBL1058296 0.80 POLB (0.34) FFAR3LMNAPLGPLATMAPT
Alcohol SCHEMBL9329911 0.80 ALDH1A1 (0.43) ESR1ESR2CYP3A4CYP2C9ALDH1A1
SCHEMBL662876 0.79 PLG (0.62) LMNAPLGPLATESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106242941-A A kind of synthetic method of Cyclopropylmetyl bromide 潍坊日兴化工有限公司 2016-12-21 CN disclosed