Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | HBB | P68871 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 5/20 | 0.64 |
| ▸ | MMP3 | P08254 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.57 |
| ▸ | FLT3 | P36888 | 3/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sciadopitisin SCHEMBL1158050 | 0.93 | MAPT (0.86) | MEN1USP2TP53MAPTKMT2A | |
| Sciadopitisin SCHEMBL30996894 | 0.93 | MAPT (0.86) | MEN1USP2TP53MAPTKMT2A | |
| Isoginkgetin SCHEMBL30293900 | 0.92 | MEN1 (0.80) | MEN1USP2TP53MAPTKMT2A | |
| Isoginkgetin SCHEMBL22459983 | 0.92 | MEN1 (0.80) | MEN1USP2TP53MAPTKMT2A | |
| Ginkgetin SCHEMBL31303838 | 0.90 | MAPT (0.86) | MEN1USP2TP53MAPTKMT2A | |
| Ginkgetin SCHEMBL888410 | 0.90 | MAPT (0.86) | MEN1USP2TP53MAPTKMT2A | |
| Ginkgetin SCHEMBL30612275 | 0.90 | MAPT (0.86) | MEN1USP2TP53MAPTKMT2A | |
| SCHEMBL17166015 | 0.88 | MEN1 (0.74) | MEN1USP2TP53MAPTKMT2A | |
| SCHEMBL22459584 | 0.88 | MAPT (0.77) | MEN1USP2TP53MAPTKMT2A | |
| Kayaflavone SCHEMBL30646162 | 0.86 | MEN1 (0.71) | MEN1USP2TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150190411-A1 | ACTIVATION OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150190411-A1 | ACTIVATION OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | GRIK5, HDAC11, GRIK1 | MEN1 3160/4885USP2 4546/4885TP53 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.