Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | HBB | P68871 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | MMP9 | P14780 | 3/20 | 0.72 |
| ▸ | MMP3 | P08254 | 2/20 | 0.72 |
| ▸ | PARP1 | P09874 | 6/20 | 0.71 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.64 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bilobetin SCHEMBL13485655 | 0.94 | MMP9 (0.80) | MEN1KMT2AMAPTUSP2TP53 | |
| Bilobetin SCHEMBL31094029 | 0.94 | MMP9 (0.80) | MEN1KMT2AMAPTUSP2TP53 | |
| Isoginkgetin SCHEMBL30293900 | 0.93 | MEN1 (0.80) | MEN1KMT2AMAPTUSP2TP53 | |
| Isoginkgetin SCHEMBL22459983 | 0.93 | MEN1 (0.80) | MEN1KMT2AMAPTUSP2TP53 | |
| Sciadopitisin SCHEMBL30996894 | 0.89 | MAPT (0.86) | MEN1KMT2AMAPTUSP2TP53 | |
| Ginkgetin SCHEMBL31303838 | 0.89 | MAPT (0.86) | MEN1KMT2AMAPTUSP2TP53 | |
| Ginkgetin SCHEMBL888410 | 0.89 | MAPT (0.86) | MEN1KMT2AMAPTUSP2TP53 | |
| Sciadopitisin SCHEMBL1158050 | 0.89 | MAPT (0.86) | MEN1KMT2AMAPTUSP2TP53 | |
| Ginkgetin SCHEMBL30612275 | 0.89 | MAPT (0.86) | MEN1KMT2AMAPTUSP2TP53 | |
| SCHEMBL16888262 | 0.88 | MEN1 (0.76) | MEN1KMT2AMAPTUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |