Sciadopitisin

Sciadopitisin

SCHEMBL1158050

COc1ccc(-c2cc(=O)c3c(O)cc(O)c(-c4cc(-c5cc(=O)c6c(O)cc(OC)cc6o5)ccc4OC)c3o2)cc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.86
MEN1 O00255 2/20 0.86
USP2 O75604 2/20 0.86
TP53 P04637 2/20 0.86
KMT2A Q03164 2/20 0.86
KDM4E B2RXH2 1/20 0.86
HPGD P15428 1/20 0.86
ALOX15 P16050 1/20 0.86
HBB P68871 1/20 0.86
HSD17B10 Q99714 1/20 0.86
APP P05067 6/20 0.70
MAOB P27338 2/20 0.69
CYP19A1 P11511 1/20 0.69
MMP3 P08254 2/20 0.66
MMP9 P14780 2/20 0.66
IP6K2 Q9UHH9 3/20 0.63
CYP1B1 Q16678 3/20 0.63
FLT3 P36888 2/20 0.63
NPC1 O15118 2/20 0.63
CYP3A4 P08684 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sciadopitisin SCHEMBL30996894 1.00 MAPT (0.86) MAPTMEN1USP2TP53KMT2A
Isoginkgetin SCHEMBL22459983 0.96 MEN1 (0.80) MAPTMEN1USP2TP53KMT2A
Isoginkgetin SCHEMBL30293900 0.96 MEN1 (0.80) MAPTMEN1USP2TP53KMT2A
Ginkgetin SCHEMBL31303838 0.96 MAPT (0.86) MAPTMEN1USP2TP53KMT2A
Ginkgetin SCHEMBL888410 0.96 MAPT (0.86) MAPTMEN1USP2TP53KMT2A
Ginkgetin SCHEMBL30612275 0.96 MAPT (0.86) MAPTMEN1USP2TP53KMT2A
SCHEMBL22459584 0.94 MAPT (0.77) MAPTMEN1USP2TP53KMT2A
SCHEMBL16888262 0.93 MEN1 (0.76) MAPTMEN1USP2TP53KMT2A
Podocarpusflavone B SCHEMBL29496271 0.92 MAPT (0.73) MAPTMEN1USP2TP53KMT2A
Podocarpusflavone B SCHEMBL27350627 0.92 MAPT (0.73) MAPTMEN1USP2TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4609911-A2 COMPOUNDS EFFECTIVE IN TREATING HEPATOTOXICITY AND FATTY LIVER DISEASES AND USES THEREOF Sinew Pharma Inc. (TW) 2025-09-03 EP claimed
US-20250000924-A1 Composition for the prevention, improvement or treatment of allergic disease comprising an extract of Taxus cuspidata as an active ingredient KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-01-02 US claimed
US-20240335404-A1 SUBSTITUTED ESTERS CONTAINING POLYOLS AND SACCHARIDES FOR TREATING HEPATOTOXICITY AND FATTY LIVER DISEASES SINEW PHARMA INC. (TW) 2024-10-10 US claimed
US-12083088-B2 Substituted esters containing polyols and saccharides for treating hepatotoxicity and fatty liver diseases SINEW PHARMA INC. (TW) 2024-09-10 US claimed
EP-4401711-A1 STABLE NON-AQUEOUS COMPOSITIONS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2024-07-24 EP claimed
WO-2023043852-A1 STABLE NON-AQUEOUS COMPOSITIONS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2023-03-23 WO claimed
CN-115813906-A Application of folium Ginkgo extract in preparing lysosome agonist and medicine or preparation for treating lysosome dysfunctional diseases 贵州医科大学 2023-03-21 CN claimed
US-20230079480-A1 STABLE NON-AQUEOUS COMPOSITIONS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-03-16 US claimed
CN-115184493-A Fingerprint detection method for active ingredients in taxus mairei medicinal material and traditional Chinese medicine decoction pieces thereof 株洲市食品药品检验所 2022-10-14 CN claimed
CN-115112783-A Ginkgo leaf detection method and construction and application of fingerprint spectrum with simultaneous reflection of multiple components 江苏康缘药业股份有限公司 2022-09-27 CN claimed
WO-2012146592-A1 CONTROLLED RELEASE TABLET OF GINKGO BILOBA EXTRACT AND PROCEDURE FOR OBTAINING IT DR. WILLMAR SCHWABE GMBH & CO. KG (DE) 2012-11-01 WO claimed
CN-102070589-B Method for extracting sciadopitysin from laxus malrel leaves NINGBO TAIKANG HONGDOUSHAN BIOLOG ENGINEERING CO LTD 2012-05-30 CN claimed
EP-2329831-A2 Stimulation of hair growth by Ginko biloba flavanoids Osteoscreen, Inc. (US) 2011-06-08 EP claimed
CN-102070589-A Method for extracting sciadopitysin from laxus malrel leaves NINGBO TAIKANG HONGDOUSHAN BIOLOG ENGINEERING CO LTD 2011-05-25 CN claimed
EP-1868625-B1 IMPROVED METHOD FOR PREPARING GINKGO EXTRACTS HAVING A LOW CONTENT OF 4'-O-METHYL PYRIDOXINE AND/OR BIFLAVONES SCHWABE WILLMAR GMBH & CO (DE) 2008-07-23 EP claimed
US-20080075794-A1 Mixture of natural plant extracts comprising extracts from Taxus and Thymus; capable of strong antimicrobial ability as well as the elimination of foul odors BAE CHANGSOON 2008-03-27 US claimed
CN-1960698-A Local slimming preparation and cosmetic containing carnitine derivative SHOWA DENKO KK (JP) 2007-05-09 CN claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
CN-1397233-A Natural Japanese yew beverage LI MEISHENG (CN) 2003-02-19 CN claimed
CN-1147552-A Jew wine and its making process ZHANG ZHENGLI (CN) 1997-04-16 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000924-A1 Composition for the prevention, improvement or treatment of allergic disease comprising an extract of Taxus cuspidata as an active ingredient SERPINB1, TSLP, CMA1 MAPT 516/4885MEN1 4738/4885USP2 1721/4885
US-20240335404-A1 SUBSTITUTED ESTERS CONTAINING POLYOLS AND SACCHARIDES FOR TREATING HEPATOTOXICITY AND FATTY LIVER DISEASES CPT1A, UGCG, UGGT1 MAPT 4443/4885MEN1 4187/4885USP2 2434/4885
US-12083088-B2 Substituted esters containing polyols and saccharides for treating hepatotoxicity and fatty liver diseases CPT1A, UGCG, UGGT1 MAPT 4443/4885MEN1 4187/4885USP2 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.