Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18724647 | 1.00 | SOAT1 (0.41) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL15426891 | 1.00 | SOAT1 (0.41) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL13284463 | 1.00 | SOAT1 (0.41) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL6276817 | 0.98 | SOAT1 (0.40) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL5488886 | 0.98 | LTA4H (0.42) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL702653 | 0.93 | LTA4H (0.42) | LTA4HTSHRCYP3A4SMYD2HTT | |
| SCHEMBL15686035 | 0.91 | SOAT1 (0.36) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL15686034 | 0.91 | SOAT1 (0.36) | SOAT1LTA4HTSHRALDH1A1LMNA | |
| SCHEMBL4341940 | 0.91 | PPARG (0.41) | SOAT1FAAHCNR1 | |
| SCHEMBL15686078 | 0.91 | SOAT1 (0.36) | SOAT1LTA4HTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103505-A2 | DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS | ESS DANIEL HALSELL (US) | 2015-07-09 | — | — | WO | disclosed |