SCHEMBL1688848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL156068	0.87	ADRB1 (0.47)	ADRB1GPR119MEN1KMT2AMAOB
	SCHEMBL14924425	0.86	GPR119 (0.47)	ADRB1GPR119MEN1KMT2AMAOB
	SCHEMBL17032190	0.84	ADRB1 (0.49)	ADRB1GPR119MEN1KMT2AMAOB
	SCHEMBL149713	0.83	ADRB1 (0.50)	ADRB1GPR119MEN1KMT2AMAPT
	SCHEMBL10642901	0.81	ADRB1 (0.53)	ADRB1GPR119MEN1KMT2AMAPT
	SCHEMBL10054726	0.81	MAPT (0.50)	MEN1KMT2AMAPTNPSR1L3MBTL1
	SCHEMBL13182959	0.81	ADRB1 (0.48)	ADRB1GPR119MEN1KMT2AMAPT
	SCHEMBL12041252	0.81	KCNH2 (0.59)	MAPTNPSR1DRD2DRD3
	SCHEMBL20231198	0.80	ADRB1 (0.47)	ADRB1GPR119MEN1KMT2AMAPT
	SCHEMBL12041222	0.79	MAPT (0.48)	MAOBMAPTNPSR1HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.