Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17013580 | 0.96 | KDM4E (0.34) | KDM4EATML3MBTL1HDAC4EDNRA | |
| SCHEMBL16889557 | 0.92 | KDM4E (0.31) | KDM4EATML3MBTL1 | |
| SCHEMBL16889322 | 0.91 | KDM4E (0.37) | KDM4EATML3MBTL1KMT2AHSD17B10 | |
| SCHEMBL16889543 | 0.89 | MAPK14 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL16890840 | 0.89 | KDM4E (0.33) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL17013581 | 0.89 | KDM4E (0.33) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL16889231 | 0.89 | — | — | |
| SCHEMBL20375705 | 0.87 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL16890841 | 0.87 | KDM4E (0.37) | KDM4EATML3MBTL1HDAC4KMT2A | |
| SCHEMBL16889416 | 0.86 | KDM4E (0.36) | KDM4EATML3MBTL1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015102118-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2015-07-09 | — | — | WO | disclosed |