SCHEMBL20375705

SCHEMBL20375705

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc(-c2cc3c4c(c2)Oc2c(cccc2-c2ccccc2)B4c2cccc(-c4ccccc4)c2O3)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
NR1H4 Q96RI1 1/20 0.32
DNMT1 P26358 3/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
SERPINE1 P05121 1/20 0.30
PPARG P37231 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20375552 0.92 DNMT1 (0.33) ALDH1A1MAPTNR1H4DNMT1
SCHEMBL16889231 0.88
SCHEMBL16889235 0.87 KDM4E (0.37) ALDH1A1
SCHEMBL20375703 0.85 ALDH1A1 (0.33) ALDH1A1MAPTRXRARXRBSERPINE1
SCHEMBL20375704 0.84 ALDH1A1 (0.33) ALDH1A1MAPTRXRARXRBSERPINE1
SCHEMBL17013580 0.83 KDM4E (0.34)
SCHEMBL16889351 0.80 KDM4E (0.31) ALDH1A1MAPT
SCHEMBL20375551 0.80 RXRA (0.34) ALDH1A1MAPTRXRARXRBSERPINE1
SCHEMBL16889557 0.79 KDM4E (0.31)
SCHEMBL20375931 0.79 ALDH1A1 (0.31) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed