Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611969 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CYP2C19TSHRSMN1; SMN2ADORA2B | |
| SCHEMBL1753327 | 0.83 | PDE4A (0.44) | ALDH1A1CYP2C19SMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL1753287 | 0.83 | PDE4A (0.44) | ALDH1A1CYP2C19SMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL1689145 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP2C19TSHRRXFP1CNR1 | |
| SCHEMBL5611448 | 0.76 | CYP2C19 (0.46) | ALDH1A1CYP2C19TSHRRXFP1MAPK1 | |
| SCHEMBL5611522 | 0.74 | GLA (0.54) | ALDH1A1CYP2C19TSHRSMN1; SMN2LMNA | |
| SCHEMBL13986117 | 0.72 | POLB (0.55) | ALDH1A1TSHRSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7117422 | 0.71 | PNP (0.51) | ALDH1A1TSHRSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7984461 | 0.70 | CNOT7 (0.52) | ALDH1A1TSHRSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7110383 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2ADORA2BRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |