Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | UBE2N | P61088 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117422 | 0.87 | PNP (0.51) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7118850 | 0.85 | BACE1 (0.49) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7111860 | 0.80 | PNP (0.45) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7117280 | 0.80 | PNP (0.45) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL4263443 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7113737 | 0.79 | PNP (0.59) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7977483 | 0.78 | CNOT7 (0.46) | SMN1; SMN2POLBHIF1AALDH1A1PNP | |
| SCHEMBL7113165 | 0.77 | PNP (0.43) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL8179399 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ADORA2BRXFP1POLBHIF1A | |
| SCHEMBL7120144 | 0.75 | PNP (0.50) | CYP11B1CYP11B2PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | claimed |
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | claimed |
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | disclosed |
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | TERT, TERF2IP, TERF2 | SMN1; SMN2 2003/4885ADORA2B 4616/4885RXFP1 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.