Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16891264 | 0.88 | LPL (0.47) | LPLLIPGF11ROCK1ESR2 | |
| SCHEMBL22753278 | 0.83 | LIPG (0.40) | LPLLIPGF11HIF1AROCK1 | |
| SCHEMBL18682054 | 0.80 | LIPG (0.59) | LPLLIPGF11ESR2CA1 | |
| SCHEMBL9901342 | 0.79 | LIPG (0.47) | LPLLIPGF11HIF1AESR2 | |
| SCHEMBL23294563 | 0.79 | LPL (0.47) | LPLLIPGF11ROCK1ESR2 | |
| SCHEMBL29914599 | 0.79 | LPL (0.47) | LPLLIPGF11ROCK1ESR2 | |
| SCHEMBL69358 | 0.78 | LIPG (0.47) | LPLLIPGF11ESR2CA1 | |
| SCHEMBL19561404 | 0.77 | LPL (0.40) | LPLLIPGF11HIF1AESR2 | |
| SCHEMBL12865795 | 0.76 | HIF1A (0.40) | LPLLIPGF11HIF1AESR2 | |
| SCHEMBL16435209 | 0.76 | LIPG (0.44) | LPLLIPGF11ESR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091010-A1 | 9,9,10,10-TETRAFLUORO-9,10-DIHYDROPHENANTHRENE HEPATITIS C VIRUS INHIBITOR AND APPLICATION THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015101215-A1 | 9,9,10,10-TETRAFLUORO-9,10-DIHYDROPHENANTHRENE HEPATITIS C VIRUS INHIBITOR AND APPLICATION THEREOF | 南京圣和药业股份有限公司 | 2015-07-09 | — | — | WO | disclosed |