Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892246 | 0.82 | P2RX7 (0.49) | P2RX7MEN1LMNAKMT2APDE4D | |
| SCHEMBL2830618 | 0.82 | MEN1 (0.51) | P2RX7MEN1LMNAKMT2APDE4D | |
| Hydrochloric Acid SCHEMBL1375056 | 0.80 | MEN1 (0.50) | P2RX7MEN1LMNAKMT2APDE4D | |
| SCHEMBL2824242 | 0.79 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL16887647 | 0.78 | LMNA (0.47) | P2RX7MEN1LMNAKMT2APDE4D | |
| SCHEMBL16886378 | 0.77 | P2RX7 (0.46) | P2RX7MEN1LMNAKMT2APDE4D | |
| SCHEMBL16891859 | 0.77 | P2RX7 (0.56) | P2RX7KDM4EMAPK1 | |
| SCHEMBL508982 | 0.77 | AR (0.51) | P2RX7MEN1LMNAKMT2APDE4D | |
| SCHEMBL509207 | 0.76 | PDE4D (0.56) | P2RX7MEN1LMNAKMT2APDE4D | |
| Oxalic Acid SCHEMBL245186 | 0.73 | LMNA (0.47) | P2RX7MEN1LMNAKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103508-A1 | CARBOCYCLIC SULFONE RORγ MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |